Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 2/20 | 0.38 |
| ▸ | MYB | P10242 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683153 | 0.84 | EGFR (0.39) | EGFRPTPN1PTAFRMYBALDH1A1 | |
| SCHEMBL27841070 | 0.83 | TUBB4A (0.38) | PTPN1ACHEMYBALDH1A1SMN1; SMN2 | |
| SCHEMBL29654713 | 0.77 | HTR2C (0.45) | — | |
| SCHEMBL515378 | 0.77 | HTR2C (0.45) | — | |
| SCHEMBL24140811 | 0.77 | KMT2A (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL18088486 | 0.77 | NPC1 (0.41) | ACHEALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6711039 | 0.76 | HTR2C (0.56) | — | |
| SCHEMBL1307935 | 0.74 | ALOX15 (0.37) | PTPN1ACHEPTAFRALDH1A1 | |
| SCHEMBL15932530 | 0.74 | NPC1 (0.38) | PTPN1ACHEPTAFRALDH1A1TSHR | |
| SCHEMBL18840154 | 0.73 | HTR2A (0.38) | ALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067416-A1 | CHEMICAL PROCESSES AND INTERMEDIATES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |