Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.56 |
| ▸ | HTR2A | P28223 | 10/20 | 0.56 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6040717 | 0.93 | HTR2C (0.47) | HTR2CHTR2AHTR2BNPC1RAB9A | |
| SCHEMBL29654713 | 0.87 | HTR2C (0.45) | HTR2CHTR2APOLBL3MBTL1NPC1 | |
| SCHEMBL515378 | 0.87 | HTR2C (0.45) | HTR2CHTR2APOLBL3MBTL1NPC1 | |
| SCHEMBL24746334 | 0.85 | HTR2C (0.41) | HTR2CHTR2AHTR2BTAAR1POLB | |
| SCHEMBL30630193 | 0.85 | HTR2C (0.41) | HTR2CHTR2AHTR2BTAAR1POLB | |
| SCHEMBL18840154 | 0.79 | HTR2A (0.38) | HTR2CHTR2ANPC1RAB9A | |
| SCHEMBL25648840 | 0.79 | ALDH1A1 (0.37) | HTR2CHTR2APOLBRAB9A | |
| SCHEMBL26122002 | 0.78 | HTR2C (0.37) | HTR2CHTR2AHTR2BNPC1RAB9A | |
| SCHEMBL2960423 | 0.78 | LMNA (0.40) | HTR2CHTR2APOLB | |
| SCHEMBL1670216 | 0.77 | MEN1 (0.47) | POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077853-A1 | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines | PFIZER INC. | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077853-A1 | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines | NOS3, NOS1, NOS2 | HTR2C 1532/4885HTR2A 816/4885HTR2B 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.