Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6070752 | 0.89 | HRH3 (0.47) | LTA4HBACE1MEN1KMT2AKDM4E | |
| SCHEMBL6069752 | 0.86 | LTA4H (0.55) | LTA4HBACE1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL6070257 | 0.85 | BACE1 (0.56) | LTA4HBACE1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL6069522 | 0.85 | BACE1 (0.56) | LTA4HBACE1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL1377022 | 0.85 | BACE1 (0.56) | LTA4HBACE1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL6070196 | 0.85 | LTA4H (0.45) | HTR7HTR1ALTA4HBACE1HRH3 | |
| Hydrochloric Acid SCHEMBL6069894 | 0.84 | LTA4H (0.44) | HTR7HTR1ALTA4HBACE1MEN1 | |
| SCHEMBL1377237 | 0.81 | LTA4H (0.47) | HTR7HTR1ADRD2LTA4HBACE1 | |
| SCHEMBL1376907 | 0.80 | HTR7 (0.40) | HTR7HTR1ADRD2HTR6LTA4H | |
| SCHEMBL6070692 | 0.80 | HRH3 (0.52) | LTA4HBACE1KDM4EHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091199-B1 | Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2006-08-15 | — | — | US | claimed |
| EP-1216249-B1 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMA INC (US) | 2003-11-19 | — | — | EP | claimed |
| US-7091199-B1 | Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1216249-B1 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMA INC (US) | 2003-11-19 | — | — | EP | disclosed |