Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377693 | 0.86 | LTA4H (0.55) | LTA4HBACE1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL7686431 | 0.85 | BACE1 (0.56) | LTA4HBACE1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL6070495 | 0.80 | HTR7 (0.40) | HTR7LTA4HBACE1MEN1KMT2A | |
| SCHEMBL7635672 | 0.80 | HRH3 (0.52) | LTA4HBACE1KDM4EHRH3ALDH1A1 | |
| SCHEMBL1376598 | 0.76 | DRD2 (0.47) | HTR1ADRD2HRH3MAOB | |
| SCHEMBL1377207 | 0.76 | DRD3 (0.53) | HTR7MEN1KMT2AHTR1ADRD2 | |
| SCHEMBL7633768 | 0.75 | MAOA (0.37) | MEN1KMT2AKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL7638803 | 0.75 | CYP1A2 (0.38) | KDM4ESMN1; SMN2MAPK1CXCR1RAB9A | |
| SCHEMBL7631973 | 0.74 | MAOA (0.38) | KDM4ESMN1; SMN2MAPK1MAOBRAB9A | |
| SCHEMBL7632638 | 0.74 | L3MBTL1 (0.47) | HTR7MEN1KMT2AHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4717306-B2 | — | — | 2011-07-06 | — | — | JP | claimed |
| JP-2003509431-A | — | — | 2003-03-11 | — | — | JP | claimed |
| EP-1216249-A2 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2002-06-26 | — | — | EP | claimed |
| WO-2001019832-A2 | THIENOISOXAZOLE PHENOXY UNSUBSTITUTED ETHYL AND PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | claimed |