Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 5/20 | 0.39 |
| ▸ | BRAF | P15056 | 5/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | GRK2 | P25098 | 1/20 | 0.37 |
| ▸ | GRK3 | P35626 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072097 | 0.83 | KDR (0.47) | PARP1MAPK14BRAFEGFRERBB2 | |
| SCHEMBL6072881 | 0.77 | LMNA (0.49) | POLB | |
| SCHEMBL18135105 | 0.76 | KDR (0.48) | KITBRAFPOLBEGFRERBB2 | |
| SCHEMBL6072600 | 0.75 | KDR (0.55) | MAPK14BRAFKDR | |
| SCHEMBL6071905 | 0.74 | PARP1 (0.40) | PARP1MAPK14BRAFKDR | |
| SCHEMBL6072019 | 0.69 | KDR (0.53) | MAPK14BRAFKDR | |
| SCHEMBL14566951 | 0.68 | KDR (0.48) | PARP1MAPK14BRAFPOLBEGFR | |
| SCHEMBL1947345 | 0.67 | DRD2 (0.45) | POLB | |
| SCHEMBL6131245 | 0.67 | MAOA (0.46) | — | |
| SCHEMBL12324805 | 0.66 | DRD2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | ADAMS JERRY L | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | CHKB, MAP3K20, MAP3K6 | PARP1 2785/4885MAPK14 152/4885KIT 966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.