SCHEMBL6131245

SCHEMBL6131245

c1ccc(CNc2ccc3c(c2)CCN3)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.46
HTT P42858 1/20 0.44
DRD2 P14416 1/20 0.44
DRD4 P21917 1/20 0.44
HSD17B3 P37058 1/20 0.43
PTPN1 P18031 1/20 0.43
PTPN11 Q06124 1/20 0.43
HAO1 Q9UJM8 1/20 0.43
DHFR P00374 1/20 0.43
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
NTRK1 P04629 2/20 0.42
ALDH1A1 P00352 1/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1947345 0.85 DRD2 (0.45) DRD2DRD4MEN1MAPTKMT2A
SCHEMBL6495200 0.81 HSD17B3 (0.48) MAOAHTTHSD17B3PTPN1PTPN11
SCHEMBL1951410 0.80 PARP11 (0.63) MAOAMAOB
SCHEMBL31341356 0.78 KIF11 (0.60) MAOAMAOB
SCHEMBL21686955 0.78 KIF11 (0.60) MAOAMAOB
SCHEMBL3694287 0.78 DRD2 (0.49) DRD2DRD4ALDH1A1MEN1MAPT
SCHEMBL1950625 0.77 MAOA (0.58) MAOAHSD17B3NTRK1MAOB
SCHEMBL30718462 0.76 NPC1 (0.64) ALDH1A1MEN1GAAMAPTBLM
SCHEMBL27370339 0.76 NPC1 (0.64) ALDH1A1MEN1GAAMAPTBLM
Hydrochloric Acid SCHEMBL8968395 0.75 MAOA (0.43) MAOAHTTHSD17B3PTPN1PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878510-B2 Method of processing silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-04-12 US disclosed
US-20050032008-A1 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. 2005-02-10 US disclosed
US-6844146-B2 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-01-18 US disclosed
US-20040058282-A1 Method of processing silver halide photosensitive material FUJI PHOTO FILM CO., LTD. 2004-03-25 US disclosed
US-6696215-B2 HIGH CONTRAST AND PHOTOSENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 2004-02-24 US disclosed
US-20040018458-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2004-01-29 US disclosed
US-20030232272-A1 Silver halide photographic light sensitive material FUJIFILM CORPORATION (JP) 2003-12-18 US disclosed
US-20030198905-A1 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. 2003-10-23 US disclosed