Toluene

Toluene

SCHEMBL607202

CC(Cl)Cl.Cc1ccccc1

nearest known ligand 0.69

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.69
ACHE P22303 4/20 0.69
LMNA P02545 4/20 0.69
ALOX12 P18054 1/20 0.69
HPGD P15428 2/20 0.42
TDP1 Q9NUW8 3/20 0.41
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
POLB P06746 1/20 0.38
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
NPSR1 Q6W5P4 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
XBP1 P17861 1/20 0.37
HTT P42858 1/20 0.37
ATM Q13315 1/20 0.37
TP53 P04637 1/20 0.37
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL8844853 0.97 ACHE (0.73) TSHRACHELMNAALOX12HPGD
Toluene SCHEMBL28398458 0.90 ACHE (0.73) TSHRACHELMNAALOX12HPGD
Toluene SCHEMBL87982 0.90 ACHE (0.73) TSHRACHELMNAALOX12HPGD
Toluene SCHEMBL6242293 0.88 ACHE (0.69) TSHRACHELMNAALOX12HPGD
Toluene SCHEMBL266608 0.85 LMNA (0.65) TSHRACHELMNAALOX12HPGD
Toluene SCHEMBL10396121 0.85 ACHE (0.65) TSHRACHELMNAALOX12HPGD
Toluene SCHEMBL5141031 0.83
P-Xylene SCHEMBL11301004 0.83 ACHE (0.61) TSHRACHELMNAALOX12TDP1
Toluene SCHEMBL10989418 0.83
Toluene SCHEMBL4429042 0.83 ACHE (1.00) TSHRACHELMNAALOX12HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108004677-B A kind of preparation method for the three-dimensional nanofiber membrane that filter efficiency is high 杭州华滤膜科技有限公司 2019-11-05 CN claimed
CN-108103666-B It is a kind of for filtering the preparation method of the three-dimensional nanofiber membrane of PM2.5 上海尔迪仪器科技有限公司 2019-09-24 CN claimed
CN-108103666-A A kind of preparation method for the three-dimensional nanofiber membrane for being used to filter PM2.5 平潭诚信智创科技有限公司 2018-06-01 CN claimed
CN-108004677-A A kind of preparation method of the high three-dimensional nanofiber membrane of filter efficiency 平潭诚信智创科技有限公司 2018-05-08 CN claimed
US-6670472-B2 Reacting 10-methoxyiminostilbene with cyanic acid (HOCN) in a solvent therefor in the presence of a mild acidic reagent to produce 10-methoxycarbamazepine MAX INDIA LIMITED (IN) 2003-12-30 US claimed
US-20030105076-A1 Process for the preparation of 10-methoxycarbamazepine JUBILANT ORGANOSYS LTD (IN) 2003-06-05 US claimed
CN-111364166-B Preparation method of flexible nanofiber composite membrane with synchronous surface function modification 厦门大学 2024-07-12 CN disclosed
WO-2024105700-A1 A METHOD FOR THE SYNTHESIS OF ANTHRANILIC AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2024-05-23 WO disclosed
CN-215499061-U Induction device for detecting side ambient light and mobile terminal 捷开通讯(深圳)有限公司 2022-01-11 CN disclosed
CN-111364166-A Preparation method of flexible nanofiber composite membrane with synchronously modified surface functions 厦门大学 2020-07-03 CN disclosed
CN-210215176-U Sun-proof heat-insulating glass plate SHENZHEN CITY YINGLIAN OPTICS TECHNOLOGY CO., LTD. 2020-03-31 CN disclosed
CN-108385282-B Preparation method of three-dimensional fiber membrane 厦门理工学院 2020-03-06 CN disclosed
CN-108004677-B A kind of preparation method for the three-dimensional nanofiber membrane that filter efficiency is high 杭州华滤膜科技有限公司 2019-11-05 CN disclosed
EP-0850232-A1 BENZOTHIAZOLONE DERIVATIVES Astra Pharmaceuticals Limited (GB) 1998-07-01 EP disclosed
EP-0476187-B1 A highly photosensitive imaging element based on a photosensitive resin AGFA GEVAERT NV (BE) 1998-05-20 EP disclosed
EP-0792280-A1 METHOD OF MAKING A LIBRARY OF COMPOUNDS Cambridge Combinatorial Ltd. (GB) 1997-09-03 EP disclosed
WO-1997010227-A1 BENZOTHIAZOLONE DERIVATIVES ASTRA PHARMACEUTICALS LIMITED (GB) 1997-03-20 WO disclosed
WO-1996016078-A1 METHOD OF MAKING A LIBRARY OF COMPOUNDS PFIZER LIMITED (GB) 1996-05-30 WO disclosed
EP-0476187-A1 A highly photosensitive imaging element based on a photosensitive resin AGFA-GEVAERT N.V. (BE) 1992-03-25 EP disclosed
US-4411985-A TRIARYLPHOSPHINES OR TRIARYLPHOSPHORANES STABILIZERS EASTMAN KODAK COMPANY (US) 1983-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105076-A1 Process for the preparation of 10-methoxycarbamazepine PARK7, BCHE, DBH TSHR 4726/4885ACHE 14/4885LMNA 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.