Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 5/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | NR2C2 | P49116 | 3/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | TAB1 | Q15750 | 3/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072032 | 0.92 | NOTUM (0.54) | RAF1NOTUMKDR | |
| SCHEMBL6071927 | 0.89 | KDR (0.52) | RAF1KDRNFKB1NR2C2NFKB2 | |
| SCHEMBL6072249 | 0.87 | HRH3 (0.48) | RAF1NOTUMKDRNFKB1NR2C2 | |
| SCHEMBL6071883 | 0.85 | KDR (0.51) | RAF1KDRNFKB1NR2C2NFKB2 | |
| SCHEMBL6072145 | 0.85 | MET (0.47) | RAF1NOTUMKDRNFKB1NR2C2 | |
| SCHEMBL6072163 | 0.84 | KDR (0.47) | RAF1KDRNFKB1NR2C2NFKB2 | |
| SCHEMBL6072190 | 0.84 | HTT (0.46) | RAF1NOTUMKDRNFKB1NR2C2 | |
| SCHEMBL6072240 | 0.83 | ALDH1A1 (0.49) | MAPK14FGFR1 | |
| SCHEMBL6072418 | 0.83 | KDR (0.47) | RAF1KDRUCHL1RIPK1MAPK14 | |
| SCHEMBL6072492 | 0.82 | ADRB2 (0.47) | KDRRIPK1HRH3FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | ADAMS JERRY L | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | CHKB, MAP3K20, MAP3K6 | RAF1 205/4885NOTUM 672/4885KDR 2025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.