SCHEMBL6072137

SCHEMBL6072137

CCCCn1cc(C(=O)O)nn1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.45
SMPD1 P17405 4/20 0.43
KDM5C P41229 1/20 0.42
HCAR3 P49019 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
GLS O94925 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
GBA1 P04062 5/20 0.40
EPHX2 P34913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23130873 0.95 SMPD1 (0.49) DPP4SMPD1KDM5CHCAR3GLS
SCHEMBL1001536 0.93 SMPD1 (0.51) SMPD1KDM5CGBA1EPHX2
SCHEMBL6071691 0.89 L3MBTL1 (0.50) DPP4KDM5CHCAR3ALDH1A1LMNA
SCHEMBL17427978 0.85 DPP4 (0.44) DPP4ALDH1A1LMNAGLS
SCHEMBL27978934 0.84 DPP4 (0.46) DPP4GLSGBA1
SCHEMBL23921581 0.83 DPP4 (0.51) DPP4ALDH1A1LMNAGLS
SCHEMBL17193769 0.82 ALDH1A1 (0.45) SMPD1ALDH1A1LMNAGLSGBA1
SCHEMBL6072289 0.82 ALDH1A1 (0.45) DPP4KDM5CALDH1A1LMNAL3MBTL1
SCHEMBL15931713 0.81 ALDH1A1 (0.60) ALDH1A1LMNA
SCHEMBL17396766 0.81 ALDH1A1 (0.44) DPP4ALDH1A1LMNAGLS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4110776-A1 NEW MACROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Les Laboratoires Servier (FR) 2023-01-04 EP disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
CN-104955332-B The method of preventing and treating arthropod insect 住友化学株式会社 2017-03-29 CN disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
CN-104955332-A Method for controlling arthropod pest SUMITOMO CHEMICAL CO 2015-09-30 CN disclosed
WO-2014119696-A1 METHOD FOR CONTROLLING ARTHROPOD PEST 住友化学株式会社 (JP) 2014-08-07 WO disclosed
US-20060160794-A1 Tachykinin receptor antagonists ELI LILLY AND COMPANY 2006-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 DPP4 4698/4885SMPD1 2426/4885KDM5C 509/4885
US-20060160794-A1 Tachykinin receptor antagonists TACR1, TACR2, PROKR1 DPP4 1786/4885SMPD1 1800/4885KDM5C 2608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.