Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072137 | 0.89 | DPP4 (0.45) | L3MBTL1DPP4ALDH1A1LMNAHCAR3 | |
| SCHEMBL23130873 | 0.88 | SMPD1 (0.49) | DPP4HCAR3KDM5CGLS | |
| SCHEMBL1001536 | 0.86 | SMPD1 (0.51) | KDM5C | |
| SCHEMBL15223688 | 0.85 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1LMNANR1H4GLS | |
| SCHEMBL6072289 | 0.85 | ALDH1A1 (0.45) | L3MBTL1DPP4ALDH1A1LMNAKDM5C | |
| SCHEMBL17630704 | 0.83 | DPP4 (0.48) | DPP4ALDH1A1LMNANR1H4KDM5C | |
| SCHEMBL20046972 | 0.82 | FABP7 (0.41) | L3MBTL1DPP4ALDH1A1LMNAHCAR3 | |
| SCHEMBL15589751 | 0.81 | DPP4 (0.50) | DPP4ALDH1A1LMNANR1H4KDM5C | |
| SCHEMBL15776049 | 0.81 | DPP4 (0.53) | DPP4ALDH1A1LMNANR1H4KDM5C | |
| SCHEMBL17625194 | 0.81 | L3MBTL1 (0.39) | L3MBTL1DPP4ALDH1A1LMNANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10487063-B2 | Preparation method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | ABA CHEMICALS (SHANGHAI) LIMITED (CN) | 2019-11-26 | — | — | US | disclosed |
| US-10487063-B2 | Preparation method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | ABA CHEMICALS (SHANGHAI) LIMITED (CN) | 2019-11-26 | — | — | US | disclosed |
| US-20180029999-A1 | Preparation Method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | ABA CHEMICALS (SHANGHAI) LIMITED (CN) | 2018-02-01 | — | — | US | disclosed |
| US-20180029999-A1 | Preparation Method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | ABA CHEMICALS (SHANGHAI) LIMITED (CN) | 2018-02-01 | — | — | US | disclosed |
| US-20180029999-A1 | Preparation Method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | ABA CHEMICALS (SHANGHAI) LIMITED (CN) | 2018-02-01 | — | — | US | disclosed |
| US-20150299143-A1 | SUBSTITUTED TRIAZOLE AND IMIDAZOLE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-10-22 | — | — | US | disclosed |
| US-20060160794-A1 | Tachykinin receptor antagonists | ELI LILLY AND COMPANY | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299143-A1 | SUBSTITUTED TRIAZOLE AND IMIDAZOLE COMPOUNDS | HDAC7, PSMB7, IKZF3 | L3MBTL1 3540/4885DPP4 2225/4885ALDH1A1 1540/4885 |
| US-20060160794-A1 | Tachykinin receptor antagonists | TACR1, TACR2, PROKR1 | L3MBTL1 3797/4885DPP4 1786/4885ALDH1A1 1815/4885 |
| US-10487063-B2 | Preparation method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | CLIC1, GRIK1, CA3 | L3MBTL1 949/4885DPP4 3317/4885ALDH1A1 1767/4885 |
| US-20180029999-A1 | Preparation Method for 1-substituted-1H-1,2,3-triazole 4-carboxylic acid | CLIC1, GRIK1, CA3 | L3MBTL1 949/4885DPP4 3317/4885ALDH1A1 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.