Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6072071 | 0.89 | SLC18A3 (0.62) | SLC18A3 | |
| Trifluoroacetic Acid SCHEMBL6072038 | 0.87 | SLC18A3 (0.49) | SLC18A3ALDH1A1MEN1KMT2AHTT | |
| Trifluoroacetic Acid SCHEMBL6071612 | 0.87 | SLC18A3 (0.54) | SLC18A3ALDH1A1MEN1KMT2AHPGD | |
| Trifluoroacetic Acid SCHEMBL6071748 | 0.84 | PLA2G7 (0.44) | AKR1C3ALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL1257872 | 0.84 | SLC18A3 (0.51) | SLC18A3AKR1C3ALDH1A1LMNAMEN1 | |
| SCHEMBL1257868 | 0.84 | SLC18A3 (0.51) | SLC18A3AKR1C3ALDH1A1LMNAMEN1 | |
| SCHEMBL1257870 | 0.84 | SLC18A3 (0.51) | SLC18A3AKR1C3ALDH1A1LMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL6071855 | 0.82 | SLC18A3 (0.45) | SLC18A3AKR1C3ALDH1A1LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL6071908 | 0.82 | SLC18A3 (0.54) | SLC18A3ALDH1A1SMN1; SMN2SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL6071354 | 0.80 | SLC18A3 (0.48) | SLC18A3ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | ACKR3, CCR5, CXCR2 | SLC18A3 2263/4885AKR1C3 159/4885ALDH1A1 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.