Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6071717 | 0.87 | TTR (0.46) | SLC18A3DRD2DRD3HTR1AAKR1C3 | |
| Trifluoroacetic Acid SCHEMBL5814484 | 0.87 | TTR (0.46) | SLC18A3DRD2DRD3HTR1AAKR1C3 | |
| Trifluoroacetic Acid SCHEMBL6072071 | 0.85 | SLC18A3 (0.62) | SLC18A3MAPK1 | |
| Trifluoroacetic Acid SCHEMBL6072334 | 0.82 | SLC18A3 (0.49) | SLC18A3ALDH1A1ADRB1NOTUMDPP4 | |
| Trifluoroacetic Acid SCHEMBL6072038 | 0.82 | SLC18A3 (0.49) | SLC18A3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Trifluoroacetic Acid SCHEMBL6071612 | 0.81 | SLC18A3 (0.54) | SLC18A3CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3106234 | 0.80 | DRD2 (0.54) | SLC18A3DRD2DRD4DRD3ADRB1 | |
| Trifluoroacetic Acid SCHEMBL6071622 | 0.80 | ALDH1A1 (0.44) | SLC18A3ALDH1A1HTR1ALMNAKDM4E | |
| Trifluoroacetic Acid SCHEMBL6071803 | 0.80 | KDM4E (0.45) | SLC18A3CYP3A4CYP2C9ALDH1A1GAA | |
| Trifluoroacetic Acid SCHEMBL6071817 | 0.79 | FAAH (0.43) | SLC18A3CYP2C19DPP4KCNH2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | ACKR3, CCR5, CXCR2 | SLC18A3 2263/4885DRD2 3087/4885DRD4 4020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.