Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6072038

O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O[C@H]1CNC[C@@H]1N1CCN(c2cccc(Cl)c2)CC1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.49
C1S P09871 1/20 0.48
HTR2A P28223 3/20 0.45
HTR1A P08908 2/20 0.45
HTR7 P34969 2/20 0.45
HTR6 P50406 2/20 0.45
HTR2C P28335 2/20 0.45
HTR2B P41595 2/20 0.45
HTR3E A5X5Y0 1/20 0.45
HTR3B O95264 1/20 0.45
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
ADRB1 P08588 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
THRB P10828 1/20 0.45
CYP2C9 P11712 1/20 0.45
SLC6A4 P31645 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6072071 0.88 SLC18A3 (0.62) SLC18A3C1S
Trifluoroacetic Acid SCHEMBL6071354 0.88 SLC18A3 (0.48) SLC18A3CYP1A2ADRB1CYP3A4CYP2D6
Trifluoroacetic Acid SCHEMBL6071723 0.88 ALDH1A1 (0.50) SLC18A3HTR2AHTR7HTR2CHTR2B
Trifluoroacetic Acid SCHEMBL6072334 0.87 SLC18A3 (0.49) SLC18A3HTR3EHTR3BADRB1HTT
Trifluoroacetic Acid SCHEMBL6071612 0.82 SLC18A3 (0.54) SLC18A3C1SCYP1A2CYP2C9CYP2C19
Trifluoroacetic Acid SCHEMBL6071855 0.82 SLC18A3 (0.45) SLC18A3HTR1ACYP1A2ADRB1CYP3A4
Trifluoroacetic Acid SCHEMBL6071817 0.77 FAAH (0.43) SLC18A3CYP2C19
Trifluoroacetic Acid SCHEMBL6071748 0.76 PLA2G7 (0.44) SIGMAR1MEN1KMT2AALDH1A1
Trifluoroacetic Acid SCHEMBL6071717 0.76 TTR (0.46) SLC18A3HTR2AHTR1A
Trifluoroacetic Acid SCHEMBL5814484 0.76 TTR (0.46) SLC18A3HTR2AHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060189628-A1 Compounds useful as chemokine receptor antagonists MILLENNIUM PHARMACEUTICALS, INC. 2006-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060189628-A1 Compounds useful as chemokine receptor antagonists ACKR3, CCR5, CXCR2 SLC18A3 2263/4885C1S 1668/4885HTR2A 2683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.