Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 11/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 11/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6072738 | 0.99 | ADRA1B (0.51) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| SCHEMBL6072910 | 0.98 | ADRA1A (0.51) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6072693 | 0.97 | ADRA1A (0.51) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| SCHEMBL6072742 | 0.92 | ADRA1B (0.44) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| SCHEMBL6072734 | 0.91 | ADRA1B (0.43) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6072701 | 0.91 | ADRA1B (0.43) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6073167 | 0.90 | ADRA1B (0.43) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| SCHEMBL6073161 | 0.90 | ADRA1A (0.44) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6072912 | 0.89 | ADRA1B (0.43) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| SCHEMBL6072696 | 0.87 | HTR1A (0.53) | ADRA1BADRA1AADRA1DHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006013445-A2 | THIAZOLIDINEDIONE DERIVATIVES AS ALPHA ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-09 | — | — | WO | claimed |
| WO-2006013445-A2 | THIAZOLIDINEDIONE DERIVATIVES AS ALPHA ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-09 | — | — | WO | disclosed |