Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232514 | 0.84 | KIF11 (0.42) | KIF11 | |
| Butylbenzyl SCHEMBL28861807 | 0.76 | KIF11 (0.56) | KIF11TRPV1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11106023 | 0.73 | KIF11 (0.48) | KIF11TRPV1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL3318601 | 0.73 | KIF11 (0.48) | KIF11 | |
| SCHEMBL11199017 | 0.72 | SPHK1 (0.50) | ALDH1A1S1PR2S1PR1S1PR3SPHK1 | |
| SCHEMBL1899105 | 0.72 | KIF11 (0.44) | KIF11 | |
| SCHEMBL8636658 | 0.70 | MMP2 (0.38) | KIF11ALDH1A1 | |
| SCHEMBL7486608 | 0.70 | KIF11 (0.42) | KIF11 | |
| SCHEMBL7486605 | 0.70 | KIF11 (0.42) | KIF11 | |
| SCHEMBL2640404 | 0.69 | PRSS1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006024453-A1 | PYRAZOLOPYRIMIDINONES AS PHOSPHODIESTERASE INHIBITORS | CTG PHARMA S.R.L. (IT) | 2006-03-09 | — | — | WO | disclosed |