Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6072733 | 0.99 | HTR7 (0.53) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL6072769 | 0.97 | HTR7 (0.53) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6072798 | 0.96 | HTR7 (0.52) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL6072530 | 0.90 | HTR1A (0.49) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL6072734 | 0.89 | ADRA1B (0.43) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL6072696 | 0.89 | HTR1A (0.53) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6073167 | 0.88 | ADRA1B (0.43) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL6072922 | 0.88 | DRD2 (0.44) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL6072742 | 0.88 | ADRA1B (0.44) | HTR7HTR1AMEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6072756 | 0.88 | HTR1A (0.52) | HTR7HTR1AMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006013445-A2 | THIAZOLIDINEDIONE DERIVATIVES AS ALPHA ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-09 | — | — | WO | claimed |
| WO-2006013445-A2 | THIAZOLIDINEDIONE DERIVATIVES AS ALPHA ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-09 | — | — | WO | disclosed |