Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28313097 | 0.79 | ASF1A (0.40) | ASF1AHTR2AALDH1A1PGRADRA2A | |
| SCHEMBL317823 | 0.79 | MTNR1A (0.47) | ASF1AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL14837249 | 0.78 | KDM1A (0.39) | ASF1AMTNR1AMTNR1B | |
| SCHEMBL6072978 | 0.74 | ASF1A (0.37) | ASF1AALDH1A1SMN1; SMN2MAPTGRIK1 | |
| SCHEMBL4631963 | 0.74 | GSK3B (0.38) | ALDH1A1SMN1; SMN2MAPTXBP1PTPN1 | |
| SCHEMBL4631968 | 0.74 | GSK3B (0.38) | ALDH1A1SMN1; SMN2MAPTXBP1PTPN1 | |
| SCHEMBL2432464 | 0.73 | ALDH1A1 (0.41) | ASF1AHTR2AALDH1A1PGRADRA2A | |
| SCHEMBL891343 | 0.73 | ALDH1A1 (0.41) | ASF1AHTR2AALDH1A1PGRADRA2A | |
| SCHEMBL28788617 | 0.73 | AKT1 (0.39) | ASF1AHTR2AALDH1A1PGRADRA2A | |
| SCHEMBL28788613 | 0.73 | AKT1 (0.39) | ASF1AHTR2AALDH1A1PGRADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856351-A | Artemisinin dimer compounds having anticancer activity | WELLS FARGO BANK, N.A. | 1999-01-05 | — | — | US | disclosed |