Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 17/20 | 0.42 |
| ▸ | CTSS | P25774 | 17/20 | 0.42 |
| ▸ | CTSK | P43235 | 16/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006426 | 0.86 | CTSK (0.53) | CTSLCTSSCTSKUSP30 | |
| SCHEMBL7011830 | 0.86 | CTSL (0.40) | CTSLCTSSCTSKUSP30CTSB | |
| SCHEMBL6072667 | 0.85 | CTSK (0.41) | CTSLCTSSCTSKUSP30CTSB | |
| SCHEMBL7006137 | 0.85 | CTSL (0.39) | CTSLCTSSCTSKUSP30CTSB | |
| SCHEMBL6073049 | 0.85 | CTSK (0.39) | CTSLCTSSCTSKUSP30CTSB | |
| SCHEMBL6072630 | 0.85 | CTSK (0.39) | CTSLCTSSCTSKUSP30CTSB | |
| SCHEMBL6072616 | 0.85 | CTSK (0.40) | CTSLCTSSCTSKUSP30CTSB | |
| SCHEMBL7012868 | 0.84 | CTSS (0.40) | CTSLCTSSCTSKUSP30 | |
| SCHEMBL7011520 | 0.84 | CTSS (0.39) | CTSLCTSSCTSKUSP30CTSB | |
| SCHEMBL7007037 | 0.84 | CTSK (0.38) | CTSLCTSSCTSKUSP30CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006505526-A | — | — | 2006-02-16 | — | — | JP | claimed |
| EP-1539178-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | claimed |
| EP-1539178-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |