Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.45 |
| ▸ | PPARA | Q07869 | 8/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.40 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073095 | 0.93 | PPARG (0.52) | PPARGPPARAMAOBCYP2C9KCNH2 | |
| SCHEMBL6073162 | 0.92 | PPARA (0.43) | PPARGPPARACYP2C9KCNH2LMNA | |
| SCHEMBL6073074 | 0.92 | PPARA (0.46) | PPARGPPARACYP2C9KCNH2LMNA | |
| SCHEMBL6073108 | 0.91 | PPARG (0.53) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL6073210 | 0.90 | PPARG (0.50) | PPARGPPARACYP2C9KCNH2LMNA | |
| SCHEMBL6072990 | 0.90 | SLC2A1 (0.48) | PPARGPPARACYP2C9KCNH2LMNA | |
| SCHEMBL6073152 | 0.89 | SLC2A1 (0.49) | PPARGPPARAMAOBCYP2C9KCNH2 | |
| SCHEMBL6073190 | 0.89 | PPARG (0.41) | PPARGPPARACYP2C9LMNASLC2A1 | |
| SCHEMBL6073306 | 0.88 | MEN1 (0.47) | PPARGPPARACYP2C9KCNH2LMNA | |
| SCHEMBL6073085 | 0.86 | LMNA (0.44) | PPARGPPARALMNASLC2A1SLC2A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |