Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.52 |
| ▸ | PPARA | Q07869 | 14/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073078 | 0.93 | PPARG (0.45) | PPARGPPARACYP2C9KCNH2SLC2A1 | |
| SCHEMBL6073210 | 0.93 | PPARG (0.50) | PPARGPPARACYP2C9KCNH2SLC2A1 | |
| SCHEMBL6072990 | 0.93 | SLC2A1 (0.48) | PPARGPPARACYP2C9KCNH2SLC2A1 | |
| SCHEMBL6073074 | 0.93 | PPARA (0.46) | PPARGPPARACYP2C9KCNH2SLC2A1 | |
| SCHEMBL6073152 | 0.93 | SLC2A1 (0.49) | PPARGPPARACYP2C9KCNH2SLC2A1 | |
| SCHEMBL6073442 | 0.91 | PPARG (0.60) | PPARGPPARACYP2C9KCNH2SLC2A1 | |
| SCHEMBL6073162 | 0.90 | PPARA (0.43) | PPARGPPARACYP2C9KCNH2SLC2A1 | |
| SCHEMBL6073190 | 0.89 | PPARG (0.41) | PPARGPPARACYP2C9SLC2A1LMNA | |
| SCHEMBL6073005 | 0.87 | PPARA (0.49) | PPARGPPARALMNA | |
| SCHEMBL6073306 | 0.86 | MEN1 (0.47) | PPARGPPARACYP2C9KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |