Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073373 | 0.89 | CFTR (0.48) | CFTRL3MBTL1MAPTLMNAATM | |
| SCHEMBL7036366 | 0.79 | SMN1; SMN2 (0.36) | CFTRCYP1A2POLBALDH1A1HSD17B10 | |
| SCHEMBL6072903 | 0.79 | HPD (0.47) | L3MBTL1MAPTLMNACYP1A2CYP2C19 | |
| SCHEMBL9076682 | 0.77 | ALDH1A1 (0.46) | L3MBTL1MAPTLMNAATMCYP1A2 | |
| SCHEMBL2403072 | 0.77 | ALDH1A1 (0.55) | CFTRL3MBTL1MAPTLMNACYP1A2 | |
| SCHEMBL6072863 | 0.76 | HPD (0.50) | L3MBTL1MAPTLMNACYP1A2CYP2C19 | |
| SCHEMBL1043699 | 0.75 | NPSR1 (0.49) | MAPTPOLBKDM4EMEN1KMT2A | |
| SCHEMBL2745486 | 0.74 | AR (0.40) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL28556385 | 0.74 | CFTR (0.44) | CFTRL3MBTL1MAPTLMNAATM | |
| SCHEMBL15898914 | 0.74 | PDE2A (0.49) | L3MBTL1CYP1A2CYP2C19CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006032987-A1 | INDOLINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF ARTERIOSCLEROSIS | PFIZER PRODUCTS INC. (US) | 2006-03-30 | — | — | WO | disclosed |