Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.42 |
| ▸ | PPARG | P37231 | 14/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073046 | 0.92 | ALDH1A1 (0.41) | PPARAPPARGLMNAMEN1ALDH1A1 | |
| SCHEMBL6073100 | 0.91 | PPARA (0.46) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL6073143 | 0.90 | PPARA (0.47) | PPARAPPARGCYP2C9KCNH2MEN1 | |
| SCHEMBL6073214 | 0.89 | PPARA (0.51) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL6073312 | 0.88 | PPARA (0.49) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL6073264 | 0.84 | PPARA (0.47) | PPARAPPARGCYP2C9KCNH2LMNA | |
| SCHEMBL6073127 | 0.83 | PPARA (0.52) | PPARAPPARGCYP2C9KCNH2LMNA | |
| SCHEMBL6073216 | 0.83 | ALDH1A1 (0.45) | PPARAPPARGCYP2C9KCNH2LMNA | |
| SCHEMBL6073224 | 0.83 | ALDH1A1 (0.48) | PPARAPPARGLMNAMEN1ALDH1A1 | |
| SCHEMBL6073229 | 0.83 | MEN1 (0.43) | PPARAPPARGCYP2C9KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |