Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073482 | 0.92 | PPARA (0.42) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL6073216 | 0.91 | ALDH1A1 (0.45) | ALDH1A1LMNASLC2A1HPGDCHEK1 | |
| SCHEMBL6073224 | 0.91 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2HPGDCHEK1 | |
| SCHEMBL6073229 | 0.90 | MEN1 (0.43) | ALDH1A1LMNASMN1; SMN2SLC2A1MEN1 | |
| SCHEMBL6073162 | 0.90 | PPARA (0.43) | LMNASLC2A1SLC2A4ARPPARG | |
| SCHEMBL6073240 | 0.89 | TDP1 (0.43) | LMNASLC2A1SLC2A4KMT2AAR | |
| SCHEMBL6073085 | 0.86 | LMNA (0.44) | ALDH1A1LMNASLC2A1SLC2A4MEN1 | |
| SCHEMBL6072990 | 0.85 | SLC2A1 (0.48) | LMNASLC2A1SLC2A4PPARGPPARA | |
| SCHEMBL6073210 | 0.83 | PPARG (0.50) | LMNASLC2A1SLC2A4PPARGPPARA | |
| SCHEMBL6073100 | 0.83 | PPARA (0.46) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |