Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073216 | 0.97 | ALDH1A1 (0.45) | ALDH1A1PPARGPPARALMNAHPGD | |
| SCHEMBL6073046 | 0.91 | ALDH1A1 (0.41) | ALDH1A1PPARGPPARALMNAHPGD | |
| SCHEMBL6073143 | 0.91 | PPARA (0.47) | ALDH1A1PPARGPPARACHEK1MAPT | |
| SCHEMBL6073133 | 0.89 | PPARG (0.49) | PPARGPPARALMNAMAPTKMT2A | |
| SCHEMBL6072990 | 0.88 | SLC2A1 (0.48) | PPARGPPARALMNA | |
| SCHEMBL6073100 | 0.88 | PPARA (0.46) | PPARGPPARA | |
| SCHEMBL6073229 | 0.88 | MEN1 (0.43) | ALDH1A1PPARGPPARALMNAKMT2A | |
| SCHEMBL6073124 | 0.85 | PPARG (0.44) | ALDH1A1PPARGPPARALMNAMAPT | |
| SCHEMBL6073085 | 0.84 | LMNA (0.44) | ALDH1A1PPARGPPARALMNAKMT2A | |
| SCHEMBL6073008 | 0.84 | PPARG (0.47) | PPARGPPARACYP3A4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |