Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073224 | 0.97 | ALDH1A1 (0.48) | ALDH1A1PPARGPPARALMNAHPGD | |
| SCHEMBL6073100 | 0.92 | PPARA (0.46) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL6073046 | 0.91 | ALDH1A1 (0.41) | ALDH1A1PPARGPPARALMNASLC2A1 | |
| SCHEMBL6073008 | 0.88 | PPARG (0.47) | PPARGPPARASLC2A1 | |
| SCHEMBL6073143 | 0.87 | PPARA (0.47) | ALDH1A1PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL6073210 | 0.87 | PPARG (0.50) | PPARGPPARALMNASLC2A1CYP2C9 | |
| SCHEMBL6073229 | 0.86 | MEN1 (0.43) | ALDH1A1PPARGPPARALMNASLC2A1 | |
| SCHEMBL6073133 | 0.86 | PPARG (0.49) | PPARGPPARALMNASLC2A1KMT2A | |
| SCHEMBL6072990 | 0.85 | SLC2A1 (0.48) | PPARGPPARALMNASLC2A1CYP2C9 | |
| SCHEMBL6073124 | 0.84 | PPARG (0.44) | ALDH1A1PPARGPPARALMNASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117743-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |