Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.43 |
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073781 | 1.00 | LGMN (0.47) | LGMNALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7138820 | 0.92 | LGMN (0.41) | LGMNALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL1664589 | 0.80 | TRIM24 (0.58) | LGMNALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL14504004 | 0.78 | LGMN (0.44) | LGMNALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5539112 | 0.77 | LGMN (0.54) | LGMNALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13067710 | 0.76 | LGMN (0.50) | LGMNALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6075003 | 0.75 | ESR1 (0.52) | LGMNALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6074997 | 0.75 | ESR1 (0.52) | LGMNALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13855691 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| Benzaldehyde SCHEMBL6075591 | 0.75 | TRIM24 (0.51) | LGMNALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022716-B2 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | WYETH (US) | 2006-04-04 | — | — | US | disclosed |
| US-20030144326-A1 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | WYETH | 2003-07-31 | — | — | US | disclosed |
| EP-1301482-A1 | CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS | Wyeth (US) | 2003-04-16 | — | — | EP | disclosed |
| US-6525202-B2 | E.g., substituted (4-amino-5-hydroxyphenyl)-oxy-)piperidinyl thiazolidin-2,4-dione; antidiabetic agents; atherosclerosis, gastrointestinal, metabolic disorders, glaucoma, neurogenetic inflammation, ocular hypertension and frequent urination | WYETH | 2003-02-25 | — | — | US | disclosed |
| US-20020028835-A1 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | WYETH | 2002-03-07 | — | — | US | disclosed |
| WO-2002006232-A1 | CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144326-A1 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | ADRB1, ADRB3, ADRB2 | LGMN 4736/4885ALDH1A1 1091/4885KDM4E 4266/4885 |
| US-20020028835-A1 | Cyclic amine phenyl beta-3 adrenergic receptor agonists | ADRB1, ADRB3, ADRB2 | LGMN 4736/4885ALDH1A1 1091/4885KDM4E 4266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.