SCHEMBL6076332

SCHEMBL6076332

FC(F)(F)c1ccc(Cc2cccs2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
TAAR1 Q96RJ0 2/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
POLB P06746 1/20 0.42
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
IDO1 P14902 2/20 0.41
SRD5A2 P31213 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
OPRK1 P41145 1/20 0.40
VKORC1 Q9BQB6 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7844700 0.83 CYP19A1 (0.49) LTA4HNPC1TAAR1MAPTNPSR1
SCHEMBL28567271 0.82 NPC1 (0.59) LTA4HNPC1RAB9ATAAR1KDM4E
SCHEMBL3236567 0.80 HPGD (0.53) NPC1RAB9ATAAR1KDM4ENPSR1
SCHEMBL6096446 0.79 MEN1 (0.49) LTA4HNPC1RAB9AL3MBTL1POLB
SCHEMBL45228 0.77 LMNA (0.50) NPC1RAB9ATAAR1KDM4EL3MBTL1
SCHEMBL2096666 0.76 SRD5A2 (0.59) LTA4HTAAR1KDM4EIDO1SRD5A2
SCHEMBL11660485 0.76 TAAR1 (0.42) LTA4HTAAR1L3MBTL1PTGS1PTGS2
SCHEMBL10953000 0.76 HPGD (0.46) LTA4HTAAR1POLBPTGS1PTGS2
SCHEMBL20738474 0.76 MEN1 (0.61) LTA4HNPC1RAB9ATAAR1MAPT
SCHEMBL10525378 0.76 L3MBTL1 (0.55) LTA4HTAAR1L3MBTL1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119096372-A Photovoltaic device and method of manufacture 第一阳光公司 2024-12-06 CN claimed
CN-116918029-A selective thermal atomic layer deposition 弗萨姆材料美国有限责任公司 2023-10-20 CN claimed
CN-116761906-A Selective plasma enhanced atomic layer deposition 弗萨姆材料美国有限责任公司 2023-09-15 CN claimed
CN-110192294-B Lithium electrode and lithium secondary battery comprising same 株式会社LG新能源 2022-09-20 CN claimed
CN-111033864-B Electrolyte for lithium metal battery and lithium metal battery comprising same 株式会社LG新能源 2022-08-12 CN claimed
CN-120129685-A Heterobicyclic compounds as EP4 receptor antagonists 深圳市原力生命科学有限公司 2025-06-10 CN disclosed
CN-116918029-A selective thermal atomic layer deposition 弗萨姆材料美国有限责任公司 2023-10-20 CN disclosed
CN-116761906-A Selective plasma enhanced atomic layer deposition 弗萨姆材料美国有限责任公司 2023-09-15 CN disclosed
CN-111763164-B Preparation method and application of ortho-carbonyl amino substituted benzene derivatives 中国医学科学院药物研究所 2023-03-10 CN disclosed
CN-110192294-B Lithium electrode and lithium secondary battery comprising same 株式会社LG新能源 2022-09-20 CN disclosed
CN-111033864-B Electrolyte for lithium metal battery and lithium metal battery comprising same 株式会社LG新能源 2022-08-12 CN disclosed
CN-107848283-B Anisotropic conductive film and display device using the same 国都化学(株) 2021-04-13 CN disclosed
US-20050059729-A1 Substituted cyclic compounds LESIEUR DANIEL (FR) 2005-03-17 US disclosed
EP-1077927-A1 NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ADIR ET COMPAGNIE (FR) 2001-02-28 EP disclosed
WO-1999058495-A1 NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ADIR ET COMPAGNIE (FR) 1999-11-18 WO disclosed
EP-0912183-A4 HETEROCYCLIC COMPOUNDS LILLY CO ELI (US) 1999-08-04 EP disclosed
EP-0912183-A1 HETEROCYCLIC COMPOUNDS ELI LILLY AND COMPANY (US) 1999-05-06 EP disclosed
WO-1997039753-A1 HETEROCYCLIC COMPOUNDS ELI LILLY AND COMPANY (US) 1997-10-30 WO disclosed
US-4837316-A ANTIULCER AGENTS FUJIREBIO KABUSHIKI KAISHA (JP) 1989-06-06 US disclosed
EP-0214823-A2 Alkylamide derivatives with H2-receptor antagonistic and cytoprotective action FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) 1987-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050059729-A1 Substituted cyclic compounds CCNY, CCNT2, TECR LTA4H 2200/4885NPC1 2639/4885RAB9A 394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.