Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076332 | 0.83 | LTA4H (0.44) | LMNAMAPTNPC1NPSR1POLB | |
| SCHEMBL20738474 | 0.79 | MEN1 (0.61) | LMNAMAPTHTTNPC1POLB | |
| SCHEMBL3385419 | 0.79 | MEN1 (0.54) | LMNAMAPTHTTCYP1A2CYP3A4 | |
| SCHEMBL5176529 | 0.76 | KMT2A (0.50) | CYP19A1LMNAMAPTALOX12HTT | |
| SCHEMBL45228 | 0.76 | LMNA (0.50) | LMNACYP2C19NPC1POLBPTGS1 | |
| SCHEMBL348623 | 0.75 | TSHR (0.52) | LMNAHTTNPSR1POLBTP53 | |
| Methyl Alcohol SCHEMBL5311361 | 0.75 | LMNA (0.50) | LMNAMAPTHTTCYP2C19NPC1 | |
| SCHEMBL10953000 | 0.75 | HPGD (0.46) | LMNACYP2C19POLBPTGS1PTGS2 | |
| SCHEMBL11660485 | 0.75 | TAAR1 (0.42) | LMNACYP2C19PTGS1PTGS2MEN1 | |
| SCHEMBL7294757 | 0.75 | CYP3A4 (0.52) | CYP19A1LMNAHTTCYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113666854-B | Preparation method of symmetrical disulfide bond-containing compound | 南京工业大学 | 2022-04-12 | — | — | CN | claimed |
| CN-113666854-A | Preparation method of symmetrical disulfide bond-containing compound | 南京工业大学 | 2021-11-19 | — | — | CN | claimed |
| US-20230357210-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2023-11-09 | — | — | US | disclosed |
| EP-3845520-B1 | SYNTHESIS OF MONOFUNCTIONAL THIURAM ACCELERATOR | GOODYEAR TIRE & RUBBER (US) | 2023-10-25 | — | — | EP | disclosed |
| US-11685712-B2 | Synthesis of monofunctional thiuram accelerator | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2023-06-27 | — | — | US | disclosed |
| CN-115916144-A | Cosmetic composition comprising a polyhydroxyalkanoate copolymer with a (non) saturated hydrocarbyl chain and a surfactant | 莱雅公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115835855-A | Cosmetic composition comprising a graft polyhydroxyalkanoate copolymer in a fatty medium | 莱雅公司 | 2023-03-21 | — | — | CN | disclosed |
| US-20230029068-A1 | SYNTHESIS OF MONOFUNCTIONAL THIURAM ACCELERATOR | THE GOODYEAR TIRE & RUBBER COMPANY | 2023-01-26 | — | — | US | disclosed |
| CN-113666854-B | Preparation method of symmetrical disulfide bond-containing compound | 南京工业大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-113666854-A | Preparation method of symmetrical disulfide bond-containing compound | 南京工业大学 | 2021-11-19 | — | — | CN | disclosed |
| CN-113121395-A | Synthesis of monofunctional thiuram accelerators | 固特异轮胎和橡胶公司 | 2021-07-16 | — | — | CN | disclosed |
| EP-3845520-A1 | SYNTHESIS OF MONOFUNCTIONAL THIURAM ACCELERATOR | The Goodyear Tire & Rubber Company (US) | 2021-07-07 | — | — | EP | disclosed |
| US-20210198194-A1 | SYNTHESIS OF MONOFUNCTIONAL THIURAM ACCELERATOR | THE GOODYEAR TIRE & RUBBER COMPANY | 2021-07-01 | — | — | US | disclosed |
| EP-0865240-B1 | USE OF 1,2,3-THIADIAZOLE CARBOXYLIC ACID (THIO)ESTERS FOR THE CONTROL OF PESTS AND 1,2,3-THIADIAZOLE CARBOXYLIC ACID (THIO)ESTERS | BAYER AG (DE) | 2001-10-04 | — | — | EP | disclosed |
| EP-0865240-A1 | USE OF 1,2,3-THIADIAZOLE CARBOXYLIC ACID (THIO)ESTERS FOR THE CONTROL OF PESTS AND NOVEL 1,2,3-THIADIAZOLE CARBOXYLIC ACID (THIO)ESTERS | BAYER AG (DE) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020465-A1 | USE OF 1,2,3-THIADIAZOLE CARBOXYLIC ACID (THIO)ESTERS FOR THE CONTROL OF PESTS AND NOVEL 1,2,3-THIADIAZOLE CARBOXYLIC ACID (THIO)ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-12 | — | — | WO | disclosed |
| EP-0665223-A1 | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357210-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE | DDT, HDHD5, HPD | CYP19A1 455/4885LMNA 4279/4885MAPT 3883/4885 |
| US-20230029068-A1 | SYNTHESIS OF MONOFUNCTIONAL THIURAM ACCELERATOR | TST, TERT, MGMT | CYP19A1 2145/4885LMNA 4647/4885MAPT 4506/4885 |
| US-11685712-B2 | Synthesis of monofunctional thiuram accelerator | TST, TERT, MGMT | CYP19A1 2145/4885LMNA 4647/4885MAPT 4506/4885 |
| US-20210198194-A1 | SYNTHESIS OF MONOFUNCTIONAL THIURAM ACCELERATOR | TST, TERT, MGMT | CYP19A1 2145/4885LMNA 4647/4885MAPT 4506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.