Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 3/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.60 |
| ▸ | WDR5 | P61964 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ATIC | P31939 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6079091 | 0.91 | PRMT1 (0.64) | PRMT1SIRT1CASP6CTDSP1CYP2C9 | |
| SCHEMBL6078502 | 0.90 | PRMT1 (0.58) | PRMT1SIRT1MEN1KMT2A | |
| SCHEMBL6078494 | 0.87 | PRMT1 (0.73) | PRMT1SIRT1CASP6CTDSP1CYP2C9 | |
| SCHEMBL6428056 | 0.87 | PRMT1 (0.58) | PRMT1SIRT1CASP6CTDSP1 | |
| SCHEMBL6078378 | 0.84 | PRMT1 (0.61) | PRMT1SIRT1MEN1KMT2A | |
| SCHEMBL6427793 | 0.84 | PRMT1 (0.55) | PRMT1SIRT1WDR5CASP6CTDSP1 | |
| SCHEMBL6079407 | 0.83 | WDR5 (0.59) | WDR5CYP2C9ATICCYP2C19HSD17B10 | |
| SCHEMBL7520951 | 0.83 | TCF4 (0.53) | PRMT1SIRT1CYP2C9CYP2C19MEN1 | |
| SCHEMBL6078120 | 0.82 | CPT2 (0.56) | PRMT1SIRT1CASP6CTDSP1 | |
| SCHEMBL6079555 | 0.81 | PRMT1 (0.57) | PRMT1SIRT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1327635-B1 | Preparation of phenylphosphate esters of 4,4'-biphenol | BROMINE COMPOUNDS LTD (IL) | 2005-08-31 | — | — | EP | claimed |
| US-7071231-B2 | Naphthalene ureas as glucose uptake enhancers | TELIK, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| EP-1181271-B1 | NAPHTHALENE UREAS AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2005-01-19 | — | — | EP | disclosed |
| US-6458998-B1 | NAPHTHALENEUREAS AS ANTIDIABETIC AGENTS | TELIK, INC. | 2002-10-01 | — | — | US | disclosed |