Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078674 | 0.96 | AKR1C3 (0.69) | AKR1C3POLBMEN1KMT2APFKFB3 | |
| SCHEMBL6079117 | 0.90 | AKR1C3 (0.79) | AKR1C3MEN1KMT2APFKFB3MAPT | |
| SCHEMBL6079407 | 0.88 | WDR5 (0.59) | AKR1C3MEN1KMT2A | |
| SCHEMBL7311403 | 0.88 | AKR1C3 (0.85) | AKR1C3POLBMEN1KMT2APFKFB3 | |
| SCHEMBL6077690 | 0.87 | MEN1 (0.74) | AKR1C3POLBMEN1KMT2A | |
| SCHEMBL6079658 | 0.87 | GAA (0.62) | AKR1C3POLBMEN1KMT2AMAPT | |
| SCHEMBL6078100 | 0.86 | TCF4 (0.68) | AKR1C3POLBMEN1KMT2AMAPT | |
| SCHEMBL788215 | 0.85 | AKR1C3 (0.67) | AKR1C3POLBMEN1KMT2APFKFB3 | |
| SCHEMBL6078502 | 0.84 | PRMT1 (0.58) | AKR1C3POLBMEN1KMT2APFKFB3 | |
| SCHEMBL6078231 | 0.83 | MEN1 (0.56) | AKR1C3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071231-B2 | Naphthalene ureas as glucose uptake enhancers | TELIK, INC. (US) | 2006-07-04 | — | — | US | disclosed |