Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080408 | 0.88 | ALDH1A1 (0.41) | TGM2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL6081485 | 0.73 | TGM2 (0.42) | TGM2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL5879169 | 0.70 | ALDH1A1 (0.46) | TGM2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL5879211 | 0.70 | ALDH1A1 (0.43) | TGM2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL5828121 | 0.69 | LMNA (0.46) | TGM2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL6081007 | 0.69 | GALR3 (0.40) | TGM2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL5879130 | 0.69 | LMNA (0.45) | TGM2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL6197547 | 0.68 | LMNA (0.47) | TGM2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL5827662 | 0.68 | PRKCA (0.49) | TGM2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL6081330 | 0.66 | LMNA (0.42) | TGM2ALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004428-A1 | Pyrrolo (3,4-c) carbazole and pyrido (2,3-b) pyrrolo (3,4-e) indole derivatives, preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2006-01-05 | — | — | US | disclosed |