Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081049 | 0.82 | MAPT (0.42) | MAPTKDM4EL3MBTL1PDE4BPDE10A | |
| Benzene SCHEMBL6594689 | 0.80 | PDE10A (0.46) | MAPTKDM4EL3MBTL1PDE4BPDE10A | |
| SCHEMBL6081015 | 0.76 | KDM4E (0.42) | MAPTKDM4EL3MBTL1PDE4BRNASEH1 | |
| SCHEMBL6081119 | 0.69 | RNASEH1 (0.44) | MAPTKDM4EL3MBTL1PDE4BRNASEH1 | |
| SCHEMBL6592438 | 0.69 | GPR35 (0.51) | MAPTKDM4EL3MBTL1PDE10ATDP1 | |
| SCHEMBL6079769 | 0.67 | KDM4E (0.38) | MAPTKDM4EL3MBTL1PDE4BRNASEH1 | |
| SCHEMBL6080920 | 0.66 | PDE10A (0.50) | MAPTKDM4EL3MBTL1PDE4BPDE10A | |
| SCHEMBL6080525 | 0.66 | PTGER1 (0.46) | MAPTL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL6079920 | 0.65 | HPGDS (0.47) | MAPTKDM4EL3MBTL1PDE10ALMNA | |
| SCHEMBL6080250 | 0.64 | DHODH (0.41) | MAPTKDM4EL3MBTL1PDE4BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | claimed |
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | MAPT 1575/4885KDM4E 1006/4885L3MBTL1 4069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.