Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063473 | 0.70 | HSD17B3 (0.44) | HSD17B3MAOBKDM4EHSD17B10GAA | |
| SCHEMBL1147722 | 0.70 | HSD17B3 (0.51) | HSD17B3MAOAKDM4EHSD17B10GAA | |
| SCHEMBL21379597 | 0.70 | HSD17B3 (0.46) | HSD17B3MAOBKDM4EHSD17B10GAA | |
| SCHEMBL20957619 | 0.69 | HSD17B3 (0.58) | HSD17B3MAOAKDM4EHSD17B10GAA | |
| SCHEMBL2454830 | 0.66 | ALDH1A1 (0.50) | HSD17B3MAOBKDM4EHSD17B10GAA | |
| SCHEMBL25190307 | 0.65 | HSD17B3 (0.42) | HSD17B3MAOBKDM4EHSD17B10GAA | |
| SCHEMBL4058366 | 0.64 | RXFP1 (0.47) | HSD17B3MAOBKDM4EHSD17B10GAA | |
| SCHEMBL5154372 | 0.63 | ALDH1A1 (0.48) | MAOBMAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL1095044 | 0.63 | HSD17B3 (0.46) | HSD17B3MAOBMAOAKDM4EHSD17B10 | |
| SCHEMBL11872682 | 0.62 | HDAC1 (0.41) | GAAALDH1A1SMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074933-B2 | Urea and thiourea derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-07-11 | — | — | US | disclosed |
| US-20040266820-A1 | Urea and thiourea derivatives | DU DANIEL Y (US) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266820-A1 | Urea and thiourea derivatives | SHBG, ZP1, ZYX | HSD17B3 2223/4885MAOB 2522/4885MAOA 2881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.