Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058366 | 0.84 | RXFP1 (0.47) | ALDH1A1TSHRPPARGNCOA2NCOA1 | |
| SCHEMBL21379597 | 0.81 | HSD17B3 (0.46) | ALDH1A1TSHRPPARGNCOA2NCOA1 | |
| SCHEMBL1147722 | 0.78 | HSD17B3 (0.51) | ALDH1A1TSHRSMN1; SMN2RXFP1KDM4E | |
| SCHEMBL3063473 | 0.78 | HSD17B3 (0.44) | ALDH1A1TSHRPPARGNCOA2NCOA1 | |
| SCHEMBL5483956 | 0.76 | MAOB (0.56) | ALDH1A1KDM4EMAPTTDP1BRD4 | |
| SCHEMBL25190307 | 0.75 | HSD17B3 (0.42) | ALDH1A1TSHRPPARGNCOA2NCOA1 | |
| SCHEMBL20957619 | 0.73 | HSD17B3 (0.58) | ALDH1A1TSHRSMN1; SMN2KDM4ELMNA | |
| SCHEMBL451687 | 0.69 | STS (0.40) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA | |
| SCHEMBL30388842 | 0.69 | MEN1 (0.54) | ALDH1A1SMN1; SMN2KDM4ELMNAHPGD | |
| SCHEMBL6267436 | 0.68 | HSD17B3 (0.41) | HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147278-B1 | COMPOUND FOR TREATING BREAST CANCER AND PROGESTIN-DEPENDENT CONDITIONS | UNIV TENNESSEE RES FOUND (US) | 2020-02-12 | — | — | EP | disclosed |
| US-20190055192-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATOR AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2019-02-21 | — | — | US | disclosed |
| US-20180116994-A1 | SARMS AND METHOD OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2018-05-03 | — | — | US | disclosed |
| US-20180071242-A1 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2018-03-15 | — | — | US | disclosed |
| EP-3147278-A1 | COMPOUND FOR TREATING BREAST CANCER AND PROGESTIN-DEPENDENT CONDITIONS | University of Tennessee Research Foundation (US) | 2017-03-29 | — | — | EP | disclosed |
| EP-2038252-B1 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | UNIV TENNESSEE RES FOUNDATION (US) | 2016-11-02 | — | — | EP | disclosed |
| EP-2054049-B1 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | UNIV TENNESSEE RES FOUNDATION (US) | 2016-04-13 | — | — | EP | disclosed |
| US-20160089356-A1 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2016-03-31 | — | — | US | disclosed |
| US-9278914-B2 | SARMs and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2016-03-08 | — | — | US | disclosed |
| US-8846756-B2 | Substituted acylanilides and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-09-30 | — | — | US | disclosed |
| US-20100249228-A1 | SARMS AND METHOD OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2010-09-30 | — | — | US | disclosed |
| US-20100204234-A1 | 17Beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Hormone-Related Diseases | UNIVERSITAET DES SAARLANDES (DE) | 2010-08-12 | — | — | US | disclosed |
| US-7772433-B2 | SARMS and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2010-08-10 | — | — | US | disclosed |
| EP-2054049-A2 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | University of Tennessee Research Foundation (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-2038252-A2 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | University of Tennessee Research Foundation (US) | 2009-03-25 | — | — | EP | disclosed |
| US-20080076828-A1 | Substituted acylanilides and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2008-03-27 | — | — | US | disclosed |
| US-20080076829-A1 | Substituted acylanilides and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2008-03-27 | — | — | US | disclosed |
| US-20080057068-A1 | SARMS and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2008-03-06 | — | — | US | disclosed |
| WO-2008024456-A2 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008008433-A2 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204234-A1 | 17Beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Hormone-Related Diseases | HSD17B1, HSD17B11, HSD17B2 | ALDH1A1 52/4885TSHR 2554/4885PPARG 1795/4885 |
| US-20080076829-A1 | Substituted acylanilides and methods of use thereof | CPT1B, MTPN, MUSK | ALDH1A1 1503/4885TSHR 3922/4885PPARG 776/4885 |
| US-20180071242-A1 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | CPT1B, MTPN, MUSK | ALDH1A1 754/4885TSHR 4464/4885PPARG 1158/4885 |
| US-20080057068-A1 | SARMS and method of use thereof | SARM1, CKMT1A; CKMT1B, TNNI3 | ALDH1A1 1873/4885TSHR 2773/4885PPARG 1051/4885 |
| US-20190055192-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATOR AND METHODS OF USE THEREOF | AR, ESRRA, SHBG | ALDH1A1 2404/4885TSHR 301/4885PPARG 49/4885 |
| US-20100249228-A1 | SARMS AND METHOD OF USE THEREOF | CPT1B, FABP4, SARM1 | ALDH1A1 1620/4885TSHR 3817/4885PPARG 428/4885 |
| US-20080076828-A1 | Substituted acylanilides and methods of use thereof | CPT1B, MTPN, MUSK | ALDH1A1 1558/4885TSHR 4035/4885PPARG 697/4885 |
| US-20160089356-A1 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | CPT1B, MTPN, MUSK | ALDH1A1 754/4885TSHR 4464/4885PPARG 1158/4885 |
| US-20180116994-A1 | SARMS AND METHOD OF USE THEREOF | SARM1, CPT1B, TNNI3 | ALDH1A1 746/4885TSHR 4605/4885PPARG 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.