Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 3/20 | 0.54 |
| ▸ | FOS | P01100 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 4/20 | 0.47 |
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | TFEB | P19484 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17263393 | 0.94 | JUN (0.61) | JUNFOSGSK3BBACE1TLR9 | |
| SCHEMBL5598952 | 0.87 | NFE2L2 (0.61) | JUNNFKB1NFE2L2TFEBHSD11B1 | |
| SCHEMBL5598954 | 0.87 | NFE2L2 (0.61) | JUNNFKB1NFE2L2TFEBHSD11B1 | |
| SCHEMBL78555 | 0.81 | CA1 (0.62) | NFKB1ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL78556 | 0.81 | CA1 (0.62) | NFKB1ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL2425317 | 0.81 | CA1 (0.62) | NFKB1ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL29386378 | 0.81 | CA1 (0.62) | NFKB1ALDH1A1TSHRRAB9ALMNA | |
| Hydrochloric Acid SCHEMBL9445634 | 0.79 | CA1 (0.60) | NFKB1ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL5666241 | 0.79 | CA1 (0.60) | NFKB1ALDH1A1TSHRRAB9ALMNA | |
| Ammonia Solution, Strong SCHEMBL6324720 | 0.79 | CA1 (0.60) | NFKB1ALDH1A1TSHRRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | JUN 4222/4885FOS 4116/4885GSK3B 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.