Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.31 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RGS12 | O14924 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847153 | 0.88 | ACKR3 (0.40) | TLR7ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7836192 | 0.85 | KDM5B (0.32) | TLR7ALDH1A1POLBADCY8ADCY1 | |
| SCHEMBL6085740 | 0.85 | KMT2A (0.34) | TLR7ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7836569 | 0.84 | GRIN1 (0.45) | TLR7ALDH1A1TPH1TPH2POLB | |
| SCHEMBL7848458 | 0.79 | MAPT (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2TPH1 | |
| SCHEMBL7846642 | 0.79 | TLR7 (0.33) | TLR7ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7848188 | 0.79 | TLR7 (0.33) | TLR7ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7848789 | 0.78 | GRIN1 (0.43) | TLR7ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7849696 | 0.77 | HSD17B10 (0.48) | ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL7846211 | 0.76 | MEN1 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2ADCY8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |