SCHEMBL6087138

SCHEMBL6087138

CCc1c(Oc2cc(C)cc(C)c2)n(Cc2cccc(Cl)n2)c(=O)[nH]c1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 4/20 0.36
DCTPP1 Q9H773 1/20 0.34
KMT2A Q03164 4/20 0.33
HPGD P15428 4/20 0.33
KDM4E B2RXH2 3/20 0.33
MEN1 O00255 3/20 0.33
HTT P42858 3/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
MAPK1 P28482 1/20 0.33
XBP1 P17861 1/20 0.33
PSMD14 O00487 1/20 0.33
TLR7 Q9NYK1 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
TPH1 P17752 1/20 0.32
TPH2 Q8IWU9 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6086584 0.88 DCTPP1 (0.34) DRD1DCTPP1KMT2AHPGDKDM4E
SCHEMBL6086926 0.85 PDE5A (0.34) KMT2AHPGDKDM4EMEN1HTT
SCHEMBL7846642 0.84 TLR7 (0.33) DRD1KMT2AKDM4EMEN1HTT
SCHEMBL6088051 0.84 GRIN1 (0.45) DRD1TLR7TPH1TPH2
SCHEMBL6086356 0.83 PDE10A (0.42) DRD1KDM4EALDH1A1
SCHEMBL6086864 0.83 HPGD (0.44) KMT2AHPGDKDM4EMEN1HTT
SCHEMBL6085740 0.80 KMT2A (0.34) KMT2AHPGDKDM4EMEN1HTT
SCHEMBL6086113 0.80 TSHR (0.35) DCTPP1KMT2AHPGDKDM4EMEN1
SCHEMBL6087044 0.79 SMN1; SMN2 (0.37) DRD1KMT2AHPGDKDM4EMEN1
SCHEMBL6086604 0.79 DRD1 (0.33) DRD1KMT2AHPGDKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6987114-B1 Antiviral pyrimidinedione derivatives and process for the preparation thereof SAMJIN PHARMACEUTICAL CO., LTD (KR) 2006-01-17 US disclosed