Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087193 | 0.84 | ROCK2 (0.36) | ROCK2DDR1GRIN1GRIN2BKDM4E | |
| SCHEMBL6086259 | 0.83 | GRIN1 (0.37) | ROCK2GRIN1GRIN2BKDM4EALDH1A1 | |
| SCHEMBL6087044 | 0.81 | SMN1; SMN2 (0.37) | KDM4EMEN1ALDH1A1KMT2ADAO | |
| SCHEMBL6086864 | 0.80 | HPGD (0.44) | KDM4EMEN1ALDH1A1KMT2ATLR7 | |
| SCHEMBL6088103 | 0.79 | ROCK2 (0.36) | ROCK2DDR1GRIN1GRIN2BHTR6 | |
| SCHEMBL6086687 | 0.79 | ROCK2 (0.36) | ROCK2DDR1GRIN1GRIN2BHTR6 | |
| SCHEMBL10204457 | 0.79 | TPH1 (0.35) | GRIN1GRIN2BKDM4EMEN1ALDH1A1 | |
| SCHEMBL7848465 | 0.78 | ROCK2 (0.32) | ROCK2 | |
| SCHEMBL6086604 | 0.78 | DRD1 (0.33) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL6087771 | 0.78 | GRIN1 (0.50) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |