Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087044 | 0.92 | SMN1; SMN2 (0.37) | DAOSMN1; SMN2KMT2ATPH1TPH2 | |
| SCHEMBL10204457 | 0.89 | TPH1 (0.35) | GRIN1GRIN2BSMN1; SMN2KMT2ARXFP1 | |
| SCHEMBL6086604 | 0.86 | DRD1 (0.33) | SMN1; SMN2KMT2ATPH1TPH2KDM4E | |
| SCHEMBL6085479 | 0.86 | MTNR1A (0.37) | GRIN1GRIN2BDAOSMN1; SMN2KMT2A | |
| SCHEMBL6086132 | 0.86 | TYMS (0.38) | SMN1; SMN2KMT2ARXFP1TPH1TPH2 | |
| SCHEMBL6086864 | 0.86 | HPGD (0.44) | KMT2AGAAKDM4EALDH1A1HPGD | |
| SCHEMBL6087627 | 0.86 | TSHR (0.34) | GRIN1GRIN2BDAOSMN1; SMN2TPH1 | |
| SCHEMBL6088310 | 0.83 | GRIN1 (0.36) | GRIN1GRIN2BDAOROCK2KMT2A | |
| SCHEMBL6086124 | 0.83 | ROCK2 (0.38) | GRIN1GRIN2BDAOROCK2KMT2A | |
| SCHEMBL6086972 | 0.82 | TYMS (0.46) | GRIN2BDAOKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |