Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CD74 | P04233 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | YWHAH | Q04917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087598 | 0.91 | MEN1 (0.37) | MTNR1AMTNR1BKDM4EALDH1A1TP53 | |
| SCHEMBL6089258 | 0.87 | KMT2A (0.41) | KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL6086464 | 0.86 | DAO (0.44) | KDM4EALDH1A1DAOKMT2A | |
| SCHEMBL6089236 | 0.86 | MTNR1A (0.48) | MTNR1AMTNR1BMIFDAOTP53 | |
| SCHEMBL6088109 | 0.85 | KMT2A (0.37) | KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL10204285 | 0.85 | TRPA1 (0.36) | KMT2A | |
| SCHEMBL7847168 | 0.84 | MTNR1A (0.49) | MTNR1AMTNR1BMIFKDM4EALDH1A1 | |
| SCHEMBL6085834 | 0.83 | IDH1 (0.41) | GRIN1GRIN2BIDH1PIK3R1PIK3CA | |
| SCHEMBL6634103 | 0.83 | KMT2A (0.38) | KDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6086784 | 0.82 | ALDH1A1 (0.36) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |