Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850932 | 0.92 | ALDH1A1 (0.34) | LMNAMAOASLC6A2ALDH1A1TP53 | |
| SCHEMBL6088530 | 0.87 | GRIN1 (0.42) | LMNAMAOASLC6A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7066800 | 0.86 | GRIN1 (0.35) | LMNAMAOASLC6A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7074091 | 0.85 | GRIN1 (0.39) | ALDH1A1SMN1; SMN2GRIN1GRIN2B | |
| SCHEMBL6086617 | 0.85 | GRIN1 (0.39) | LMNAMAOASLC6A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6088065 | 0.84 | GRIN1 (0.38) | ALDH1A1SMN1; SMN2GRIN1GRIN2B | |
| SCHEMBL12829055 | 0.83 | MAOB (0.36) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6086654 | 0.83 | LMNA (0.36) | LMNAMAOASLC6A2ALDH1A1NPSR1 | |
| SCHEMBL7844254 | 0.82 | LMNA (0.33) | LMNAMAOASLC6A2TP53HBB | |
| SCHEMBL6087128 | 0.81 | TPH1 (0.34) | ALDH1A1TP53SMN1; SMN2GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |