Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 2/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CD74 | P04233 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6085479 | 0.90 | MTNR1A (0.37) | MTNR1AMTNR1BHSD17B10DAOGRIN1 | |
| SCHEMBL6086864 | 0.88 | HPGD (0.44) | HSD17B10KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL6087044 | 0.86 | SMN1; SMN2 (0.37) | HSD17B10DAOKMT2AMEN1ALDH1A1 | |
| SCHEMBL6087014 | 0.85 | DAO (0.46) | DAOKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL6087695 | 0.85 | GRIN1 (0.44) | GRIN1GRIN2BKMT2APIK3R1PIK3CA | |
| SCHEMBL6086447 | 0.84 | MTNR1A (0.49) | MTNR1AMTNR1BHSD17B10MIFCMA1 | |
| SCHEMBL7836586 | 0.83 | HSD17B10 (0.51) | MTNR1AMTNR1BHSD17B10MIFCMA1 | |
| SCHEMBL6087450 | 0.82 | MAPT (0.42) | KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL6085671 | 0.82 | GRIN1 (0.44) | GRIN1GRIN2BALDH1A1POLB | |
| SCHEMBL6086259 | 0.81 | GRIN1 (0.37) | HSD17B10DAOGRIN1GRIN2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |