Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086864 | 0.86 | HPGD (0.44) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6087425 | 0.85 | TYMS (0.45) | TYMSGRM2TSHRHCRTR1HCRTR2 | |
| SCHEMBL6087044 | 0.85 | SMN1; SMN2 (0.37) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7847016 | 0.84 | TYMS (0.46) | TYMSTSHRHCRTR1HCRTR2ALOX5AP | |
| SCHEMBL6087627 | 0.83 | TSHR (0.34) | TSHRALDH1A1MAPTKDM4EGRIN2B | |
| SCHEMBL6088338 | 0.82 | TYMS (0.44) | TYMSTSHRHCRTR1HCRTR2ALOX5AP | |
| SCHEMBL6087460 | 0.82 | TYMS (0.44) | TYMSGRM2TSHRHCRTR1HCRTR2 | |
| SCHEMBL6086259 | 0.82 | GRIN1 (0.37) | ALDH1A1KMT2AKDM4EGRIN2BDAO | |
| SCHEMBL6086604 | 0.82 | DRD1 (0.33) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6087014 | 0.81 | DAO (0.46) | TSHRALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |