Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086864 | 0.90 | HPGD (0.44) | HPGDKDM4EKMT2AHTTMEN1 | |
| SCHEMBL6087450 | 0.87 | MAPT (0.42) | HPGDKDM4EKMT2AHTTMEN1 | |
| SCHEMBL6087044 | 0.86 | SMN1; SMN2 (0.37) | DAOHPGDKDM4EKMT2AHTT | |
| SCHEMBL6088271 | 0.85 | NPBWR1 (0.35) | PDE10AHPGDKDM4EKMT2AHTT | |
| SCHEMBL6087068 | 0.85 | DAO (0.46) | DAOPDE10AHPGDKDM4EKMT2A | |
| SCHEMBL6086483 | 0.85 | MTNR1A (0.50) | DAOKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL6086356 | 0.84 | PDE10A (0.42) | PDE10AKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL6087695 | 0.82 | GRIN1 (0.44) | KMT2A | |
| SCHEMBL6085671 | 0.82 | GRIN1 (0.44) | HPGDALDH1A1MAPK1 | |
| SCHEMBL10204457 | 0.82 | TPH1 (0.35) | HPGDKDM4EKMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |