Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.43 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.39 |
| ▸ | CYBB | P04839 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846575 | 0.87 | HPD (0.41) | TLR7KMT2AMEN1CYP3A4POLB | |
| SCHEMBL7848789 | 0.85 | GRIN1 (0.43) | GRIN1GRIN2BCNOT7PKMMAPK10 | |
| SCHEMBL6087076 | 0.84 | GRIN1 (0.43) | GRIN1GRIN2BPKMTLR7POLB | |
| SCHEMBL7845907 | 0.81 | MAPT (0.36) | MAPK10KMT2AMEN1POLB | |
| SCHEMBL7847168 | 0.81 | MTNR1A (0.49) | GRIN1GRIN2BKMT2APOLB | |
| SCHEMBL7836190 | 0.81 | MAPT (0.36) | MAPK10KMT2AMEN1 | |
| SCHEMBL7848710 | 0.80 | MTNR1A (0.37) | PKMKMT2AMEN1 | |
| SCHEMBL7835808 | 0.79 | GRIN1 (0.43) | GRIN1GRIN2BCNOT7PKMMAPK10 | |
| SCHEMBL7836192 | 0.78 | KDM5B (0.32) | KDM5BTLR7POLB | |
| SCHEMBL7846719 | 0.78 | TYMS (0.41) | GRIN2BOPRM1OPRD1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |