Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28774738 | 0.81 | TAS1R3 (0.51) | TDP1ALDH1A1MAPK1L3MBTL1POLB | |
| SCHEMBL28416132 | 0.79 | MMP9 (0.47) | L3MBTL1POLBKMT2A | |
| SCHEMBL29237378 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1POLBRAB9A | |
| SCHEMBL5339626 | 0.76 | CA12 (0.52) | ALDH1A1MAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL24103891 | 0.75 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1HDAC1KMT2A | |
| SCHEMBL5701779 | 0.75 | PPARG (0.58) | PPARGTDP1MAPK1PPARDPPARA | |
| SCHEMBL4424175 | 0.75 | DHODH (0.48) | ALDH1A1L3MBTL1POLBRAB9ANPC1 | |
| SCHEMBL813251 | 0.73 | CA12 (0.50) | ALDH1A1MAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL29283528 | 0.73 | KMT2A (0.51) | ALDH1A1MAPK1L3MBTL1POLBMEN1 | |
| SCHEMBL13395861 | 0.72 | CA12 (0.49) | ALDH1A1MAPK1L3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7081465-B2 | Alpha-substituted naphthyloxy omega-substituted alky/aryl amino-substituted alkane derivatives as agent for treatment or prophylaxis of diabetes and related metabolic disorders | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-07-25 | — | — | US | claimed |