Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | KIF11 | P52732 | 1/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TLR4 | O00206 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21542305 | 0.87 | KIF11 (0.56) | KDM4ETAAR1KIF11KMT2ATLR4 | |
| SCHEMBL1368828 | 0.82 | KIF11 (0.60) | KDM4EKIF11LMNACYP1A2KMT2A | |
| SCHEMBL30675253 | 0.82 | RAPGEF4 (0.61) | TAAR1ABCG2IDO1KMT2ARAPGEF4 | |
| SCHEMBL29793056 | 0.82 | KIF11 (0.60) | KDM4EKIF11LMNACYP1A2KMT2A | |
| SCHEMBL392473 | 0.82 | RAPGEF4 (0.61) | TAAR1ABCG2IDO1KMT2ARAPGEF4 | |
| SCHEMBL11476804 | 0.81 | ALDH1A1 (0.52) | KDM4ETAAR1ABCG2PTGS1PTGS2 | |
| SCHEMBL22926673 | 0.78 | TAAR1 (1.00) | KDM4ETAAR1LMNACYP1A2KMT2A | |
| SCHEMBL27894486 | 0.78 | CYP1A1 (0.48) | KDM4ETAAR1KIF11ABCG2CYP1A1 | |
| SCHEMBL3954788 | 0.78 | ABL1 (0.58) | KIF11PTGS1PTGS2LMNAIDO1 | |
| SCHEMBL1931380 | 0.78 | NPSR1 (0.60) | KDM4EKIF11PTGS1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812055-A | Compound for organic electroluminescent device, organic electroluminescent device comprising same | 陕西莱特迈思光电材料有限公司 | 2021-05-18 | — | — | CN | disclosed |
| US-20060167055-A1 | Non-nucleoside reverse transcriptase inhibitors | MEDIVIR AB (SE) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167055-A1 | Non-nucleoside reverse transcriptase inhibitors | POLR2H, POLR2E, POLR1E | KDM4E 2439/4885TAAR1 1702/4885KIF11 2436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.