Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 9/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.45 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 1/20 | 0.37 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086605 | 0.85 | HPGD (0.42) | TLR7TPH1TPH2KDM4EALDH1A1 | |
| SCHEMBL6086609 | 0.84 | GRIN1 (0.45) | GRIN1GRIN2BNOX4TLR7GABRA1 | |
| SCHEMBL6086685 | 0.84 | HPGD (0.33) | TLR7TPH1TPH2KDM4EALDH1A1 | |
| SCHEMBL7845199 | 0.84 | GRIN1 (0.45) | GRIN1GRIN2BNOX4TLR7GABRA1 | |
| SCHEMBL6088008 | 0.83 | DPP4 (0.36) | TPH1TPH2KDM4EALDH1A1HPGD | |
| SCHEMBL6086939 | 0.82 | GRIN1 (0.43) | GRIN1GRIN2BNOX4TLR7GABRA1 | |
| SCHEMBL6086546 | 0.81 | TPH1 (0.34) | GRIN1GRIN2BTLR7TPH1TPH2 | |
| SCHEMBL6086282 | 0.80 | DAO (0.45) | TLR7DAOKDM4EALDH1A1HPGD | |
| SCHEMBL6087851 | 0.80 | GRIN1 (0.45) | GRIN1GRIN2BNOX4TLR7TPH1 | |
| SCHEMBL6086314 | 0.80 | HTT (0.33) | TLR7DAOKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |