Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | TPH1 | P17752 | 1/20 | 0.40 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086545 | 0.85 | HPGD (0.43) | TPH1TPH2ADORA3MEN1TSHR | |
| SCHEMBL6088087 | 0.84 | GRIN1 (0.45) | GRIN1GRIN2BTLR7TPH1TPH2 | |
| SCHEMBL6086113 | 0.84 | TSHR (0.35) | GLATLR7TPH1TPH2ADORA3 | |
| SCHEMBL7845277 | 0.83 | GRIN1 (0.45) | GRIN1GRIN2BGLATLR7GABRA5 | |
| SCHEMBL6086514 | 0.83 | PDE10A (0.40) | TPH1TPH2MEN1TSHRMAPK1 | |
| SCHEMBL6087645 | 0.81 | GRIN1 (0.44) | GRIN1GRIN2BTLR7GABRA5GABRA1 | |
| SCHEMBL6087421 | 0.81 | SMN1; SMN2 (0.37) | GRIN1GRIN2BTPH1TPH2ADORA3 | |
| SCHEMBL6086995 | 0.80 | POLB (0.35) | ADORA3DAOMEN1TSHRMAPK1 | |
| SCHEMBL6086507 | 0.79 | DAO (0.45) | ADORA3DAOMEN1TSHRMAPK1 | |
| SCHEMBL6088051 | 0.79 | GRIN1 (0.45) | GRIN1GRIN2BGLATLR7TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |