Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 1/20 | 0.34 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086367 | 0.92 | TYMS (0.37) | HPGDTSHRMAPT | |
| SCHEMBL6087279 | 0.92 | ALDH1A1 (0.33) | HPGDTSHRKMT2AKDM4EMEN1 | |
| SCHEMBL6085643 | 0.92 | GRIN1 (0.36) | KMT2AALDH1A1DAOSMN1; SMN2GRIN1 | |
| SCHEMBL6086605 | 0.92 | HPGD (0.42) | TPH1TPH2HPGDTSHRKMT2A | |
| SCHEMBL7837061 | 0.91 | TPH1 (0.30) | TPH1TPH2HPGDTSHRALDH1A1 | |
| SCHEMBL6086149 | 0.90 | MTNR1A (0.35) | HPGDTSHRKMT2AKDM4EMEN1 | |
| SCHEMBL6085665 | 0.89 | TSHR (0.34) | TPH1TPH2HPGDTSHRKMT2A | |
| SCHEMBL6086282 | 0.87 | DAO (0.45) | HPGDTSHRKMT2AKDM4EMEN1 | |
| SCHEMBL6086939 | 0.86 | GRIN1 (0.43) | HPGDALDH1A1PKMPOLBGRIN1 | |
| SCHEMBL6086384 | 0.85 | MTNR1A (0.47) | HPGDKMT2AALDH1A1HSD17B10DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |